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EFFYDRAL / EFFERHYDRAN Effervescent Tablets for Calves and Pigs
- The product has been specially developed to correct dehydration electrolyte loss and metabolic acidosis, particularly when these disturbances arise as a consequence of diarrhoea. Oral rehydration capacity of Effydral/Efferhydran is based on the following therapeutical principles:
- it must provide sodium to restore extracellular fluid volume,
- it must provide energy in the form of glucose or lactose as the animal is normally placed on a diet of water,
- sodium absorption (and therefore water absorption) is enhanced by various agents such as amino acids (glycine) and short-chain fatty acids (citrate),
- The acidosis that generally accompanies dehydration-inducing diarrhoea must be corrected by providing bicarbonate (hydrogen carbonate).
Description
Effydral / Efferhydran is, an effervescent tablet to be dissolved in water. The resulting isotonic oral dehydrations solution has the following composition:
| Constituent | Quantity (mmol/l) | |
| Sodium | 120 | |
| Potassium | 15 | |
| Chloride | 55 | |
| Bicarbonate + citrate | 80 | * |
| Lactose | 90 | ** |
| Glycine | 30 |
** 90 mmol lactose is equivalent to 180 mmol glucose
INDICATIONS
Effydral solution corrects dehydration, electrolyte loss and metabolic acidosis, particularly when these disturbances arise as a consequence of diarrhoea.
CONTRAINDICATIONS
If the gastro-intestinal tract is completely obstructed, care should be taken when administering oral solutions.
ADVERSE REACTIONS
When used according to the instructions, no side-effects have been observed or are to be expected.
TARGET SPECIES
Effydral has been specially developed for the treatment of diarrhoea in calves and pigs.
DOSAGE, ROUTE AND METHOD OF ADMINISTRATION
Effydral is intended for oral administration only.
Effydral solution is prepared by adding one effervescent tablet to 1 litre lukewarm (about
37°C) water. The solution should be freshly made up just prior to feeding, using clean water
and utensils.
If solution has been stored in a refrigerator (2-8oC), gently warm to 37oC before
administration.
Calves
Calves with diarrhoea: Treatment should commence immediately diarrhoea is noticed.
Withdraw milk or milk replacer and feed 2 or 3 litres of Effydral solution, depending on calf
size or severity of diarrhoea, twice daily for two days.
During the next two days, feed 1 or 1.5 litres of Effydral solution mixed with an equal
quantity of milk or milk replacer. Normal feeding can then usually be resumed.
In cases of severe dehydration, the Effydral solution should be administered in three or four
feeds per day. If necessary, the solution may be administered by stomach tube. Normally,
calves can be fed Effydral solution exclusively for up to four days without harmful effects.
Bought-in calves: Instead of milk or milk replacer, the first feed on arrival should consist of 2
litres of Effydral solution. The second feed should contain 1 litre of Effydral solution mixed
with 1 litre of milk or milk replacer. Thereafter feed as normal.
Pigs
Birth to weaning: When scour occurs, make Effydral available ad libitum in a clean utensil.
The amount consumed per pig depends on age.
Weaned pigs: Allow ad libitum consumption up to a maximum of 1 litre per pig per day.
Provide untreated water at all times.
WITHDRAWAL PERIOD
Zero days.
SHELF LIFE
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf-life after dilution or reconstitution according to directions: 24 hours.
SPECIAL STORAGE PRECAUTIONS
Do not store above 25°C.
Once dissolved in water, store in a refrigerator (2-8°C).
Any medicated water which is not consumed within 24 hours should be discarded.
SPECIAL WARNINGS
Wash hands after use.
Solutions should be prepared using clean water and feeding utensils should be kept clean.
Replace with fresh solution every 24 hours.
If Effydral is administered in too concentrated a solution to an animal, free access to drinking
water should be provided.
Whenever possible adequate colostrum should be fed to animals.
Avoid over feeding of milk or milk replacer.
For oral administration only.
In very severe cases of dehydration accompanied by shock, additional intravenous fluid
therapy may be required with an appropriate parenteral solution.
Any unused veterinary medicinal product or waste materials derived from such veterinary
medicinal products should be disposed of in accordance with local requirements.
OTHER INFORMATION
ATCvet Code QA07CQ02
Nature and composition of immediate packaging
Aluminium tubs covered with aluminium foil. One cardboard box contains 48 individually packed tablets.
National label conditions must be observed by country.
