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Equest Oral Gel 18.92 mg/g, for horses and ponies
- Unique moxidectin based wormer. Offers single dose control of all stages of cyathostomin nematodes (Strongylidae), including the harmful and potentially fatal larval stages encysted in the horses gut wall, as well as other species of nematodes and bots.
- Reduces nematode egg-re appearance for at least 90 days, providing the longest dosing interval of any routine wormer.
- Kills ingested larvae for a further two weeks after treatment, reducing the number that actually burrow into and damage the horse’s gut wall.
- Palatable 'melt-in-the-mouth' gel formula presented in an easy to use dial a dose syringe to ensure horses receive their required dose.
- Moxidectin has no confirmed resistance in horses in Europe.
Sweden: Cydectin Vet
Description
Equest is an oral yellow gel that contains by gram:
| Active substances: | |
|---|---|
| Moxidectin | 18.92 mg |
| Excipients: | |
| Benzyl alcohol | 37.84 mg |
| Disodium Edetate | 0.24 mg |
| Excipients qsp to 1 g | |
Moxidectin is a parasiticide active against a wide range of internal and external parasites and is a second generation macrocyclic lactone of the milbemycin family. Moxidectin interacts with GABA and glutamate gated chloride channels. The net effect is to open the chloride channels on the postsynaptic junction to allow the inflow of chloride ions and induce an irreversible resting state. This results in flaccid paralysis and eventual death of parasites exposed to the drug.
Moxidectin is absorbed following oral administration with maximum blood concentrations being achieved 8 hours post application. The elimination half life is 28 days.
INDICATIONS
In horses and ponies for treatment of infections caused by moxidectin sensitive strains of:
- Large strongyles:
- Strongylus vulgaris (adults and arterial stages)
- Strongylus edentatus (adults and visceral stages)
- Triodontophorus brevicauda (adults)
- Triodontophorus serratus (adults)
- Triodontophorus tenuicollis (adults)
- Small strongyles (adults and intraluminal larval stages)
- Cyathostomum spp.
- Cylicocyclus spp.
- Cylicostephanus spp.
- Cylicodontophorus spp.
- Gyalocephalus spp.
- Ascarids:
- Parascaris equorum (adults and larval stages)
- Other species:
- Oxyuris equi (adults and larval stages)
- Habronema muscae (adults)
- Gasterophilus intestinalis (L2, L3)
- Gasterophilus nasalis (L2, L3)
- Strongyloides westeri (adults)
- Trichostrongylus axei (adult stages)
The product has a persistent efficacy of two weeks against small strongyles. The excretion of small strongyle eggs is suppressed for 90 days.
The product is effective against (developing) intramucosal L4 stages of small strongyles. At 8 weeks after treatment, early (hypobiotic) EL3 stages of small strongyles are eliminated.
CONTRAINDICATIONS
Do not administer to young foals less than 4 months old.
Do not administer in case of known hypersensitivity to the active ingredient or to any other milbemycins and to any other ingredients of the veterinary medicinal product.
ADVERSE REACTIONS
Ataxia, depression, abdominal pain, muscle tremor, flaccid lower lip and swelling of the muzzle could be observed on very rare occasions. These adverse effects are usually transient and disappear spontaneously in most cases. Adverse reactions by overdose may occur at 2 times the recommended dose in foals and 3 times the recommended dose in adults. There is no specific antidote.
TARGET SPECIES
Horses and ponies.
DOSAGE FOR EACH SPECIES, ROUTE AND METHOD OF ADMINISTRATION
A single oral dose of 400 µg moxidectin/kg bodyweight using the calibrated syringe.
Hold the syringe with the capped end pointing to the left and so that you can see the weight measurements and tick marks (small black lines). Each tick mark relates to 25 kg of body weight. Turn the dial ring until the left side of the ring lines up with the weight of the animal.
Use of a scale or weight tape is recommended to ensure accurate dosing.
A single syringe treats a 575 kg horse.
WITHDRAWAL PERIOD
Meat and offal: 32 days.
SHELF LIFE
Shelf-life of the veterinary medicinal product as packaged for sale: 24 months.
Shelf life after opening: 6 months.
SPECIAL STORAGE PRECAUTIONS
Do not store above 25 °C.
SPECIAL WARNINGS
Special precautions for use in animals
To avoid overdosing, care should be taken to accurately dose foals, especially low body weight foals or pony foals.
Do not use the same syringe to treat more than one animal unless horses are
running together or in direct contact with each other in the same premises. Equest has been formulated specifically for use in horses only.
Dogs or cats may be adversely affected by the concentration of moxidectin in this veterinary medicinal product if they are allowed to ingest spilled paste or have access to used syringes. Neurological signs (such as ataxia, muscle tremor and convulsions) and digestive clinical signs (such as hypersalivation) were recorded.
The veterinary medicinal product has been shown to be safe for use in pregnant and lactating mares.
Special precautions to be taken by the person administering the product to the animals
Avoid direct contact with skin and eyes.
The use of protective gloves is recommended.
Wash hands or any exposed area after use.
Do not smoke, drink or eat while handling the veterinary medicinal product.
In the event of eye contact, flush the eye with copious amounts of clean water and seek medical advice.
The product is toxic for fish and aquatic organisms. Do not contaminate ponds, waterways or ditches with the veterinary medicinal product or used syringes.
Any unused product or waste materials should be disposed of in accordance with national requirements.
OTHER INFORMATION
ATCvet code: QP54AB02
Nature and composition of immediate packaging
High density polyethylene syringe containing 12.2g of gel
with a graduated plunger with a low density polyethylene piston and cap packed as follows:
Box containing one syringe
Box containing 10 individually boxed syringes
National label conditions must be observed by country.
