< Back to the list of products
Poulvac Hitchner B1, Lyophilisate for reconstitution for eye drops solution, nasal drops solution, oral
Description
| Active Ingredients | Per dose |
|---|---|
| Live Newcastle Disease Virus, strain B1 | 105.5 – 107.2EID50 |
INDICATIONS
For the active immunisation of chickens to reduce clinical signs due to infection with
Newcastle disease virus.
The onset of immunity is from three weeks after vaccination. Immunity has been shown to
last for at least 6 weeks.
CONTRAINDICATIONS
Do not vaccinate unhealthy birds.
ADVERSE REACTIONS
Reactions to vaccination occur seldom after intranasal, intraocular or drinking water administration. Mild respiratory distress is observed in up to 4% of birds vaccinated by the spray route. These symptoms typically appear within 4 to 9 days of the administration of the vaccine and may last several days.
TARGET SPECIES
Chickens.
DOSAGE, ROUTE AND METHOD OF ADMINISTRATION
For drinking water, spray, intranasal or eye drop administration.
Drinking Water:
For birds 2 weeks of age or older.
Never use less than one dose per bird. Discontinue any drinking water medication 24 hours
before vaccination.
- Water containing a high level of free chlorine should not be used. A general indication is that if chlorine can be detected in the water by smell or by taste it could deactivate the living virus. If so 1 pint (500 ml) of skimmed milk should be thoroughly mixed into every 5 gallons (20 litres) of water before adding the vaccine. Only perfectly clean and rust free utensils and drinkers (preferably plastic) should be used and disinfectants and detergents must not be used for cleaning. Ensure that there is enough drinking trough space to allow all birds immediate access to the vaccine. No untreated water should be available until the treated water has been consumed. Withhold the water 1-2 hours before vaccination to stimulate thirst.
- Remove the aluminium seal from the vaccine vial. To dissolve the vaccine pellet, the rubber stopper should then be removed whilst the vial is immersed in a plastic measuring jug containing one litre (approximately 1 quart) of clean cool water. Half fill the vial with water, replace the stopper and shake to dissolve any remaining vaccine.The vaccine concentrate should then be added to and thoroughly mixed with sufficient drinking water to last for approximately 2 hours.
- The approximate drinking water requirements are:-
-
Quantity per 1,000 birds Age of Birds Litres Gallons First week 2-4 ½-1 Weeks 2-4 8-10 2-2½ Weeks 5-7 12-16 3-4 8 weeks and over 18-20 4½-5 - Distribute the diluted vaccine evenly in the drinkers.
- Do not expose prepared drinking water vaccine to sunlight.
- Return to regular watering only after the vaccine water has been consumed.
- The vaccine solution is best divided so that the drinkers are charged at least twice with the vaccine to ensure a more widespread uptake.
- If nipple drinkers are employed, ensure that header tanks are continually refilled with water containing vaccine.
- The vaccine may be used in automatic watering equipment. However, the main supply should only be turned on when all the vaccine-treated water has been consumed.
Spray:
For birds 4 weeks of age or older
Hitchner B1 vaccine, has been successfully used in most types of spray equipment, the droplet sizes varying from coarse (Knapsack) to very fine (aerosol).
The vaccine should be dissolved as described under drinking water administration. The vaccine concentrate should then be added to the water in the sprayer tank and thoroughly mixed.
Intranasal:
For use in birds from one day of age.
Reconstitute the vaccine as directed below.
Fit the drop dispenser on the bottle.
Place finger over one nostril of the bird, allow one drop of the vaccine to fall into the other nostril.
Vaccination is completed when the vaccine is inhaled into nasal cavity. Do not release the bird until this occurs.
Eye drop:
For use in birds from one day of age.
Reconstitute the vaccine as directed below.
Fit the drop dispenser on the bottle.
Hold the bird so that one eye is pointed upwards and allow one drop of vaccine to fall into the eye.
Reconstitution for intranasal and eye drop routes:
Remove the aluminium foil and rubber stopper from the vaccine vial and add sterile diluent to half fill the vial.
Replace the rubber stopper and shake so that all the vaccine material is completely dissolved.
WITHDRAWAL PERIOD
Zero days.
SHELF LIFE
Shelf-life of the veterinary medicinal product as packaged for sale: 30 months.
Shelf-life after reconstitution according to directions: use immediately.
SPECIAL STORAGE PRECAUTIONS
Store and transport at +2°C to +8°C.
Protect from light.
Do not freeze
SPECIAL WARNINGS
Special precautions for use in animals
It is accepted that spray administration offers benefits over water administration in terms of
ease of application and percentage of birds vaccinated. Nevertheless, greater secondary
problems can result under certain management conditions. Spray vaccination should not be
used if inter-current infection is suspected.
Do not use in birds in lay.
When administered by eye drop at day of age, no information is available on the safety and
efficacy from the use of this vaccine with any other except Poulvac IBMM and Poulvac
MDVac (frozen wet) administered concurrently by eye drop and by injection, respectively, or
Poulvac Bursine 2 administered by eye drop within 7 days.
When administered by eye drop at 4 weeks of age, no information is available on the safety
and efficacy from the use of this vaccine with any other except Poulvac ILT, Poulvac AE and
Poulvac Bursine 2 by eye drop.
No information is available on the compatibility of this vaccine with any other except in the
situations and with the products described above.
Do not mix with any other vaccine/immunological product except Poulvac IBMM, Poulvac
ILT, Poulvac AE and Poulvac Bursine 2 when administering by eye drop. No information is
available on the safety and efficacy of mixing this vaccine with any other for any other route
of administration.
No adverse reactions exceeding those reported in section were recorded following
administration of a tenfold overdose by the oral, intranasal or eye drop routes. The
administration of a tenfold overdose by the spray route results in an increased incidence of
respiratory distress and may result in mortality rates of up to 8 %.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Live Newcastle disease virus may cause conjunctivitis in man. When administering vaccine
by the spray method operators must protect eyes and nose by wearing standard goggles and
mask or a full face mask that comply with BS EN 166:2002 and BS EN 149:2001.
Dispose of waste material by boiling, incineration or immersion in appropriate disinfectant in
accordance with national requirements.
OTHER INFORMATION
ATCVet Code: QI01AD06
Nature and composition of immediate packaging
The lyophilised vaccine is bottled in Type 1 Borosilicate Glass bottles with aluminium seals
and rubber stoppers.
Fill volume for the 1,000, 2,500 or 5,000 dose presentation is 3.4 to 3.7 ml, 7.8 to 8.2 ml for
the 10,000 dose presentation and 20.0 to 23.0 ml the 25,000 dose presentation.
Not all pack sizes may be marketed.
National label conditions must be observed by country.
