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Poulvac IB Primer, Oral Solution or Spray Solution for Chickens.

1 Jones R.J., Worthington K.J., Capua I., Naylor C.J., "Efficacy of live infectious bronchitis vaccines against a novel European genotype Italy 02", Veterinary Record, 2005, 156, 646-647
Wijmenga W.J.H., "Results of pan-european survey on infectious bronchitis and efficacy of vaccination against challenge with QX-like IBV", FDAH technical bulletin, 2006

Description

Oral solution or spray solution after reconstitution of the freeze-dried vaccine in water for chickens

Active Ingredients:Per dose
Infectious bronchitis virus strain H120 103.0 - 105.4 EID50
Infectious bronchitis virus strain D274 clone 103.0 - 105.4 EID50

INDICATIONS

For active immunisation of chickens to reduce upper respiratory tract infections caused by strains of the Massachusetts serotype and Dutch variant strains D207/D274.
The onset of immunity is from 27 days post vaccination.
Protection of chicks will be of approximately 16 weeks duration at which age the chickens may be vaccinated with an appropriate inactivated IBV vaccine product.

CONTRAINDICATIONS

Do not use in sick chickens.

ADVERSE REACTIONS

A mild vaccination reaction can be observed in the form of transient, slight respiratory symptoms such as occasional sneezing and coughing. No harmful clinical effects have been observed. Tracheal histopathology revealed very low scores in the post vaccination period.

TARGET SPECIES

Chickens from one day of age.

DOSAGE, ROUTE AND METHOD OF ADMINISTRATION

One dose per chicken to be administered with drinking water or by spray. The quantity of water to be used depends on the method of administration. Never use less than 1 dose per bird.
Drinking water
Discontinue any drinking water medication 24 hours before vaccination. Water containing a high level of free chlorine should not be used. A general indication is that if chlorine can be detected in the water by smell or taste it could deactivate the living virus.
If so, half a litre (1 pint) of skimmed milk should be thoroughly mixed into every 20 litres (5 gallons) of water or skimmed milk powder added at a rate of two grams per litre of water before adding vaccine.
Only perfectly clean and rust free utensils and drinkers (preferably plastic) should be used, and disinfectants must not be used for cleaning. Ensure that there is enough drinking trough space to allow all birds immediate access to the vaccine. No untreated water should be available until the treated water has been consumed.
Withhold drinking water for 2 hours before vaccination to stimulate thirst. Remove the aluminium seal from the vaccine vial. To dissolve the vaccine pellet, the rubber stopper should then be removed whilst the vial is immersed in a plastic measuring jug containing 1 litre (approximately 1 quart) of clean cool water. Half fill the vial with water, replace the stopper and shake to dissolve any remaining vaccine.
The vaccine concentrate should then be added to and thoroughly mixed with sufficient drinking water to last for approximately 2 hours.
The approximate drinking water requirements for vaccination can be calculated from the age of the birds. Use as many litres of water as the age of the birds in days, per 1000 birds, up to a maximum of 40 litres per 1,000 birds.
Distribute the diluted vaccine evenly in the drinkers. Do not expose prepared drinking water vaccine to sunlight.
Return to regular watering only after the vaccine water has been consumed. The vaccine solution is best divided so that the drinkers are charged at least twice with vaccine to ensure a more widespread uptake.
If nipple drinkers are employed, ensure that header tanks are continually refilled with water containing vaccine.
The vaccine may be used in automatic watering equipment. However, the main supply should only be turned on when all the vaccine treated water has been consumed.
NB: Check that birds are never left without water after vaccine treatment.
Spray
Poulvac IB primer has been used in most types of spray equipment. The equipment should provide a droplet size of 0.12 to 0.15 mm diameter. The distance from the spraying head to the bird must be approximately 50 cm. Use 0.15 to 0.5 litres of water per 1,000 birds depending upon the type of spray equipment to be used.
The vaccine should be dissolved as described under drinking water administration. The vaccine concentrate should then be added to the water in the sprayer tank and thoroughly mixed.

WITHDRAWAL PERIOD

Zero days

SHELF LIFE

Shelf-life of the veterinary medicinal product as packaged for sale: 18 – 36 months. (May vary per country)
Reconstituted vaccine should be used within 4 hours.

SPECIAL STORAGE PRECAUTIONS

Store and transport refrigerated (2oC - 8oC).
Protect from light.
Do not freeze.

SPECIAL WARNINGS

It is accepted that spray administration offers benefits over water administration in terms of ease of application and percentage of birds vaccinated. Nevertheless, greater secondary problems may result under certain management conditions. Spray vaccination should not be used if intercurrent infection is suspected. It is important to consult your veterinary adviser or Fort Dodge Animal Health technical staff before using the spray technique.
Efficacy against infectious bronchitis caused by the 4/91 (793B) UK variant IB strain has not been demonstrated.
Maternally derived antibody (MDA) can interfere with the development of active immunity. Where it is likely that recent field infection or vaccination of the parent flock has stimulated a high antibody titre and consequently a high level of MDA, the timing of the vaccination programme should be planned accordingly.
Special precautions for use in animals
Care should be taken in the planning and implementation of vaccination programmes as vaccine virus may spread from vaccinates to non-vaccinated chickens. It is recommended that all chickens on a site be vaccinated with this product.
Can be used before the onset of lay in chickens intended for breeding.
Safety in hens in lay has not been demonstrated. Not to be used for birds in lay (or breeding birds).
No information is available on the safety and efficacy from the concurrent use of Poulvac IB Primer with any other except Poulvac NDW and Poulvac SHS, administered by the spray route to maternal antibody positive chicks. It is therefore recommended that no other vaccines than these should be administered within 14 days before or after vaccination with the product.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
It is recommended to spray vaccinate in a sealed cabinet. Alternatively, the eyes and face of vaccination staff should be protected by a full facemask approved to BS2091 (e.g. a Siebe- Gorman vista type) and eye goggles should be worn.
A helmet with filtered air circulation may be used instead of goggles and mask.
On completion operators should wash and disinfect hands in an approved disinfectant.
On completion of vaccination, all empty or part-used vials, any residual vaccine and the materials used for vaccination should be burnt or disinfected in a disinfectant approved for use under the Diseases of Animals (Approved Disinfectants) Orders.

OTHER INFORMATION

ATCvet code: QI01AD07
Nature and composition of immediate packaging
Nature: Type I glass (Ph.Eur) vial
Closure: Butyl rubber (Ph.Eur) and aluminium tear-off cap.
Content: Freeze-dried pellet.
Pack size: Pack of 10 vials containing 1,000, 2,000 or 5,000 doses.
Not all pack sizes may be marketed.
National label conditions must be observed by country.

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